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EEG as a Predictor of Medication Response – Updated December 2025

EEG as a Predictor of Medication Response:An Updated Review and Analysis Thomas F. Collura Original Paper: February 2012Updated: December 2025 (in collaboration with Claude.ai) Abstract This report examines the evidence that the human electroencephalogram (EEG) can be used to help predict medication response in clients with mental health concerns. This updated review incorporates research published

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Advances in EEG Analysis – Homomorphic Deconvolution of EEG using ICA and sLORETA

We have implemented a system that performs homomorphic deconvolution of resting EEG samples, using a built-in ICA, frequency-domain averaging, sLORETA, and source localization to deconvolve EEG rhythms into individual sources and patterns.  The signature captures the morphology of one “event” being produced by that brain source. The question being asked is, if the brain were

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THe RDoC Framework: Four Dimensions graph

Symptoms, Disorders, Functions, and the NIH Research Domain Criteria

Symptoms, Disorders, Functions, and the NIH Research Domain Criteria There are historically two basic approaches to evaluation and treatment of mental and emotional disorders, and although they are in some conflict, it is possible to combine them to ensure best practices.  These are the disorder-oriented symptom-based approach, epitomized by the DSM-V and its associated practice

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Z-Score Neurofeedback: Retrospect and Prospect: Reviewing the Literature

“The simplest type of breakdown exhibits itself as an oscillation in a goal-seeking process which appears only when that process is actively invoked.”   — Norbert Wiener (1988) The Human use of Human Beings: Cybernetics and Society”, p. 1163, Da Capo Press. Z-score neurofeedback (ZNF) is an advanced EEG-based biofeedback technique that uses real-time statistical comparisons

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